Gut Bacteria And Health
Intestinal bacteria influence your mental health
Gut Bacteria And Health Tests carried out in two groups of Europeans, who number just over 1,000 participants, showed that people suffering from depression lack two types of intestinal bacteria.
Not many people know it, but the human brain, as well as its functioning, is intimately linked with the intestine, and the extraordinary amount of microorganisms that made the human intestinal tract its permanent home.
In recent years, various investigations have shown, with increasing force, that there is a strong bidirectional communication between the neuronal, endocrine and immune systems and the microbiota.
One of the most intriguing and controversial are the relationships that would exist between intestinal microbial metabolism and mental health and controversial in the investigation of microbiomes. Until now, this relationship had been in small groups of animals. But now, a research published in the journal Nature Microbiology, proved in a large group of humans that this relationship is tangible.
“It’s the first real test of how the chemicals in a microbe might affect mood in humans,” says John Cryan, a neuroscientist at University College Cork in Ireland, who has been one of the most vocal advocates of a microbial connection. -cerebral.
To find this relationship, Jeroen Raes, a microbiologist at the Catholic University of Leuven in Belgium, teamed up with 14 colleagues from various European universities to investigate this phenomenon. To do this, they closely monitored 1054 Belgians they had recruited to evaluate a “normal” microbiome. Some in the group, 173 in total, had been diagnosed with depression or had performed poorly in a quality of life survey.
What the investigations did was to compare the presence of four types of intestinal bacteria between the participants who reported a higher quality of life and those who had been diagnosed with depression, the most common mental disorder in industrialized societies.
To verify that depression was the variable that varied the microbiome of the participants, the scientists measured factors such as age, sex or the use of antidepressants, all of which influence the microbiome.
“Four significantly depleted taxa were identified in participants with depression / undergoing treatment with antidepressants,” the researchers reported. These four types of bacteria were found in a good number of people with high quality of life.
“Faecalibacterium and Coprococcus butyrate producing bacteria were systematically associated with indicators of higher quality of life. Together with Dialister, Coprococcus spp. They also ran out of depression, even after correcting the confounding effects of antidepressants, “the paper reads.
Also, the researchers found that depressed people had an increase in the bacteria involved in Crohn’s disease (a disease that chronically swells the bowel).
The study, John Cryan told Science, “really pushes the field where it has been” with small studies of depressed people or experiments with animals.